Structure-activity relationships (SAR) analysis plays a vital role in drug discovery. By systematically modifying the chemical structure of a lead compound and measuring the resulting biological activity, researchers determine the key structural features responsible for desired effects. This insight informs further development of novel therapeutic

The management of chronic pain often involves a multi-faceted approach, incorporating pharmacological interventions designed to modulate various neurological pathways involved in pain perception and transmission. Commonly employed drug classes include nonsteroidal anti-inflammatory drugs (NSAIDs), which exert their symptom-altering effects by inhib